Table 4.
Intraoperative Data
| Normocapnia (n= 38) | Hypercapnia (n= 40) | P values | |
|---|---|---|---|
| Duration of anesthesia (min) | 171 (150, 201) | 164 (135, 187) | 0.358 |
| Duration of surgery (min) | 149 (121,174) | 157 (135,187) | 0.358 |
| Duration of pneumoperitoneum (min) | 143 (120, 170) | 133 (105, 160) | 0.322 |
| Total fluid infusion | |||
| Crystalloid solution (mL) | 1000 (1000, 1300) | 1000 (1000, 1500) | 0.835 |
| Colloidal solution (mL) | 500 (500, 500) | 500 (250, 500) | 0.169 |
| Red blood cells | 0 | 0 | |
| Urine output (mL) | 275 (150, 400) | 200 (150, 300) | 0.556 |
| Estimated blood loss (mL) | 30 (30, 50) | 50 (30, 50) | 0.751 |
| Intraoperative drugs | |||
| Propofol (mg) | 150 (120, 200) | 150 (108, 200) | 0.460 |
| Sufentanil (μg) | 25 (25, 30) | 27 (20, 30) | 0.747 |
| Atracurium (mg) | 22.2 ± 7.3 | 24.4 ± 4.3 | 0.207 |
| Sevoflurane (mL/h) | 16.6 (14.0, 19.8) | 15.8 (12.3, 18.7) | 0.351 |
| Remifentanil (mg) | 1.2 (1.0, 1.6) | 1.2 (1.0, 1.4) | 0.135 |
| Atropine, n (%) | 8 (21.1%) | 13 (32.5%) | 0.255 |
| Vasopressor drugs, n (%) | 24 (63.2%) | 31 (77.5%) | 0.165 |
| Hypotensor, n (%) | 0 (0) | 0 (0) | |
| Adverse events, n (%) | |||
| Hypotension | 20 (52.6%) | 8 (20.0%) | 0.003 |
| Hypertension | 5 (13.2%) | 6 (15.0%) | 0.815 |
| Bradycardia | 15 (39.5%) | 11 (27.5%) | 0.262 |
| Tachycardia | 4 (10.5%) | 1 (2.5%) | 0.325 |
| Hypoxemia | 1 (2.6%) | 1 (2.5%) | 1.000 |
Note: Data are presented as the mean ± SD, median (interquartile range), or number of patients (%). P-value as a result of t-test, U Mann–Whitney or χ²-test.