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. 2024 Nov 19;14:28652. doi: 10.1038/s41598-024-74891-7

Fig. 1.

Fig. 1

Sequence analysis and binding capacity of aptamer pool after 7 rounds of selection. (A) Sequence analysis. (A1) (pseudo-)phylogenetic trees generated based on the multiple sequence alignment (MSA). (A2) Multiple sequence alignment (MSA) of particular aptamers within indicated clusters (flanking fragments, identical in all aptamers, were excluded from analysis). A3 Number of occurrences in the entire aptamer pool (based on NGS results). (B) Binding capacity of representative aptamers determined using ELISA.