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. 2024 Nov 20;14(50):37087–37103. doi: 10.1039/d4ra06697a

Common global diseases caused by bacterial infection, with the main sources of infection, key effects, annual deaths, and common detection methods.

Pathogen Source Effects Annual deaths Detection method Reference
E. coli O157 : H7 Raw vegetables, undercooked beef unpasteurized milk, fruit juice Diarrhea, stomach pain, hemorrhagic colitis, and HUS 200 000 Conventional methods, ELISA PCR, biosensors, etc. 3
Salmonella Raw and undercooked egg, fruits and vegetables Diarrhea, fever, and stomach cramps 155 000 RT-PCR, SPR, QCM, impedimetry, etc. 17
18
Shigella Salads and unclean water Diarrhea, fever, and stomach cramps 1.1 million PCR, rep-PCR, culture methods, immunological methods etc. 19
17
Clostridium botulinum Meat, poultry, cooked dried beans and gravies Diarrhea and stomach cramps PCR, nested PCR, real-time PCR 20
Norovirus Eating food or drinking liquids contaminated by an infected person Vomiting, diarrhea, and stomach cramps 200 000 Real-time PCR 10
Staphylococcus aureus Cooked ham, salads, and bakery products High fever, nausea, and vomiting 19 832 Conventional methods, molecular biological methods, optical immunoassays 9
Bacillus cereus Raw plant foods, such as rice, potatoes, peas, beans, and spices Intestinal illnesses with nausea, vomiting, and diarrhea Immunosensors and DNA biosensors etc. 21
Listeria monocytogenes Raw, unpasteurized milks and cheeses, ice cream, raw or processed vegetables, fruits Fever, muscle aches, headache 260 Conventional culture methods, PCR etc. 22