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. 2024 Sep 11;37(11):1757–1768. doi: 10.1021/acs.chemrestox.4c00207

Table 2. Phosphorus Nucleophiles.

name structure CAS no. EC3 (%) pEC3 ClogP
triphenyl phosphite (PhO)3P 14 101-02-0 1.4 2.34 5.73
isodecyl phosphite (Me2CH(CH2)7O)3P 15 25448-25-3 20 1.40 12.0
diisodecylphenyl phosphite (Me2CH(CH2)7O)2POPh 16 25550-98-5 41 1.03 10.09
triisotridecyl phosphite (Me2CH(CH2)10O)3P 17 77745-66-5 92.1 0.83 12.0
triethyl phosphite (EtO)3P 18 122-52-1 19/20 in GPMT (5% injection induction, 100% topical induction, 100% challenge) N/A 0.51