Table 7. Anacardic Acid, Cardanol, and Cardol^a.

^aFor anacardic acid, which would be mainly ionized at physiological pH, the logP value is based on the carboxylate ion. The σ(meta) value of 0.09 given by Hansch et al.¹⁸ is used for the ionized CO₂H group. For the R group, a σ⁺ value of −0.29, based on the value given by Hansch et al.¹⁸ for n-butyl, is used.

^bThese figures are calculated by addition of toxic units: 100/EC3_mix = %_A/EC3_A + %_B/EC3_B...

^cRounded average of figures given by Symes and Dawson³² and Caillol.³³

^dLogP values calculated manually by the method of Leo and Hansch.³⁴ Details of these calculations are given in SI3.