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. 2024 Nov 15;17:8861–8879. doi: 10.2147/JIR.S486412

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© 2024 Yang et al.

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Network pharmacological analysis of CAR-regulated AGE-RAGE signaling pathway. (A) Venn analysis on putative targets of MIRI, ferroptosis, as well as CAR-related genes. (B) KEGG enrichment analysis of putative targets of CAR for treating MIRI. (C) Western blotting was performed to detect the expression levels of AGE-RAGE signaling pathway-related proteins in myocardial tissues. n = 6 per group. *P < 0.05 vs Sham group, ^#P < 0.05 vs I/R group.