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. 2024 Nov 20;13(11):659–672. doi: 10.1302/2046-3758.1311.BJR-2023-0361.R2

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© 2024 Mo et al.

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Fig. 7 — Knockdown of PA28γ alleviates osteoarthritis (OA) after destabilized medial meniscus (DMM) surgery. a) PA28γ representative immunofluorescence staining images and quantitative data of knee joint tissue obtained from Ad-shControl and Ad-shPA28γ mice eight weeks after DMM surgery, measuring scale = 100 μm, magnification: ×200 (n = 3, ****p < 0.0001). b) Osteoarthritis Research Society International (OARSI) score of mouse knee joint (n = 6, ***p < 0.001, ****p < 0.0001). c) Haematoxylin and eosin (HE) staining images of knee joint tissue obtained from Ad-shControl and Ad-shPA28γ mice eight weeks after DMM surgery, measuring scale = 100 μm. d) Safranin O/solid green staining images of knee joint tissue obtained from Ad-shControl and Ad-shPA28γ mice eight weeks after DMM surgery, measuring scale = 100 μm. e) Toluidine blue staining images of knee joint tissue obtained from Ad-shControl and Ad-shPA28γ mice eight weeks after DMM surgery, measuring scale = 100 μm, magnification: ×400.