Fig. 5.

RES regulates the level of ferroptosis in the lung tissues of HS rats. (A) Expression and distribution of the SLC7A11, GPX4, HO-1, and Nrf2 proteins in the lung trachea determined using IHC. (B–E) Quantitative statistics of IHC test results. (F) Western blotting for SLC7A11, GPX4, HO-1, and Nrf2 proteins. (G–J) Quantitative statistics of optical density values of protein bands determined using western blotting. (K) Lung tissue Fe²⁺ content. **P < 0.01, *P < 0.05, compared with the control group; ##P < 0.01, #P < 0.05, compared with the model group