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. 2024 Nov 20;23:385. doi: 10.1186/s12944-024-02372-x

Table 3.

Subgroup analysis of the relationship between cotinine and RC

Characteristicb Q1 Q2 Q3 Q4 Q5 p-inta
Age strata 0.76
  < 60 years ref -0.35(-1.41, 0.72) 0(-1.20, 1.21) 0.09(-1.03, 1.21) 2.05(1.01, 3.09)
  ≥ 60 years ref 0.34(-1.03, 1.70) 1.5(-0.52, 3.51) 1.44(-0.55, 3.43) 2.75(0.97, 4.53)
Sex 0.02
 Male ref -0.05(-1.37, 1.28) 0.8(-0.77, 2.38) 1.15(-0.41, 2.71) 2.22(0.73, 3.71)
 Female ref -0.1(-1.32, 1.12) -0.02(-1.22, 1.18) -0.49(-1.73, 0.75) 3.22(1.79, 4.65)
Race 0.73
 Other/multiracial ref 0.11(-1.77, 1.98) 0.25(-1.74, 2.25) 0.7(-1.33, 2.72) 1.08(-1.36, 3.52)
 Non-Hispanic black ref -0.17(-2.56, 2.21) 0.12(-2.42, 2.65) -0.47(-2.88, 1.93) 1.53(-0.90, 3.96)
 Non-Hispanic white ref -0.18(-1.19, 0.84) 0.52(-0.73, 1.78) 0.52(-0.73, 1.77) 2.86(1.76, 3.96)
Alcohol use 0.55
 Non drinker ref 0.69(-1.11, 2.50) 0.05(-1.68, 1.78) 0.91(-1.67, 3.49) 4.32(0.74, 7.90)
 Drinker ref -0.23(-1.13, 0.67) 0.5(-0.66, 1.65) 0.37(-0.69, 1.43) 2.39(1.39, 3.39)
Income level 0.58
 Poor ref 1.01(-2.59, 4.62) -0.88(-4.47, 2.71) 0.98(-2.73, 4.70) 2.78(-1.01, 6.57)
 Not poor ref -0.17(-1.03, 0.70) 0.6(-0.51, 1.70) 0.45(-0.63, 1.53) 2.59(1.62, 3.55)
Education attainment 0.05
 High school or below ref -0.13(-1.87, 1.62) -0.02(-1.84, 1.80) -1.02(-2.82, 0.79) 1.71(-0.03, 3.46)
 College graduate or above ref -0.17(-1.14, 0.81) 0.49(-0.64, 1.62) 1.2(-0.13, 2.52) 2.98(1.81, 4.16)
Cancer 0.84
 No ref 0.03(-0.86, 0.92) 0.44(-0.66, 1.54) 0.46(-0.56, 1.49) 2.6(1.56, 3.64)
 Yes ref -0.72(-4.19, 2.74) 0.32(-3.41, 4.04) 0.69(-3.18, 4.57) 1.06(-3.24, 5.36)
Heart disease 0.25
 No ref -0.1(-1.01, 0.81) 0.61(-0.42, 1.64) 0.62(-0.36, 1.61) 2.49(1.58, 3.40)
 Yes ref 0.01(-3.30, 3.32) -1.03(-4.74, 2.67) -1.48(-5.41, 2.45) 2.54(-1.54, 6.63)
Diabetes 0.79
 No ref -0.07(-0.95, 0.82) 0.57(-0.49, 1.63) 0.47(-0.48, 1.42) 2.72(1.79, 3.64)
 Yes ref -0.38(-4.71, 3.95) -1.67(-7.90, 4.56) 1.8(-2.53, 6.14) 0.35(-3.64, 4.34)

ap-int: p for interaction

bAdjusted for: Age, Sex, BMI, Race, Income level, Education attainment, Alcohol use, MET, Cancer, Heart disease, Diabetes