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. 2024 Nov 20;25:783. doi: 10.1186/s13063-024-08620-w

Table 2.

Biological outcome measures

Biological outcome measure Number of samples per session Sampling time points per session Sampling procedure
Autonomic nervous system
 sAA 7 Baseline, − 1, + 1, + 10, + 20, + 30, + 45 min Saliva sample
 HR - Continuously ECG
 HRV - Continuously ECG
HPA axis
 Cortisol 7 Baseline, − 1, + 1, + 10, + 20, + 30, + 45 min Saliva sample
Inflammatory system
 IL-6 3  − 1, + 30, + 90 min Peripheral blood sample
 IL-6 expression 3  − 1, + 30, + 90 min Peripheral blood sample
 IL-1β expression 3  − 1, + 30, + 90 min Peripheral blood sample
 NF-кB expression 3  − 1, + 30, + 90 min Peripheral blood sample
 IкB expression 3  − 1, + 30, + 90 min Peripheral blood sample

ECG electrocardiogram, HPA axis hypothalamus-pituitary adrenal axis, HR heart rate, HRV heart rate variability, IкB I kappa B kinase, IL Interleukin, NF-кB nuclear Factor kappa B, sAA salivary alpha-amylase