In vitro antibacterial activity of the synthesized derivatives (MIC: μg mL−1).
Strain | Drug-sensitive bacteria | Drug-resistant bacteria | |||||
---|---|---|---|---|---|---|---|
S. aureus | B. subtilis | E. coli | P. aeruginosa | MRSA | K. pneumonia | VRE | |
5a | 64 | 128 | >128 | >128 | >128 | >128 | >128 |
5b | 128 | >128 | >128 | 128 | 128 | >128 | >128 |
5c | 128 | 64 | 128 | 128 | >128 | >128 | >128 |
5d | 128 | 128 | >128 | 128 | >128 | >128 | 128 |
5e | 32 | 64 | 128 | 128 | >128 | >128 | >128 |
5f | 32 | 64 | 128 | >128 | 128 | 128 | 128 |
5g | 32 | 32 | 64 | >128 | 64 | >128 | >128 |
5h | 64 | 128 | 128 | 128 | 128 | >128 | 128 |
5i | 64 | 64 | 128 | >128 | >128 | 128 | 128 |
5j | 128 | 64 | >128 | 128 | 128 | 64 | 128 |
5k | 64 | 64 | 128 | 128 | >128 | >128 | >128 |
5l | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
5m | 16 | 32 | 32 | 64 | 32 | 64 | >128 |
5n | 16 | 16 | 32 | 128 | 16 | 64 | >128 |
5o | 8 | 32 | 16 | 64 | 16 | 64 | 128 |
5p | 4 | 8 | 4 | 64 | 8 | 128 | >128 |
KAN a | 1 | 0.5 | 1 | 4 | 1 | 4 | 8 |
KAN: kanamycin.