Protein binding of 5p and control group after 4 h of incubation in plasma.
Entry | % average recovery | SDa | % unbound | % bound | SD |
---|---|---|---|---|---|
5p | 73.5 | 15.6 | 7.32 | 92.6 | 0.002 |
Controlb | 71.2 | 12.3 | 0.45 | 99.5 | 0.001 |
Results are expressed as the mean ± S.D. of four independent experiments (n = 4).
Control: sarolaner, >99% protein bound.