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. 2024 Nov 1. Online ahead of print. doi: 10.1039/d4md00670d

Protein binding of 5p and control group after 4 h of incubation in plasma.

Entry % average recovery SDa % unbound % bound SD
5p 73.5 15.6 7.32 92.6 0.002
Controlb 71.2 12.3 0.45 99.5 0.001
a

Results are expressed as the mean ± S.D. of four independent experiments (n = 4).

b

Control: sarolaner, >99% protein bound.