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. 2024 Nov 20;10(47):eadr5807. doi: 10.1126/sciadv.adr5807

Fig. 1. Overall structure of the TSC:WIPI3 complex.

Fig. 1.

(A) High-resolution reconstruction (composite) of the TSC:WIPI3 complex. Scale bar, 5 nm. (B) Cartoon model of the TSC:WIPI3 complex [oriented as in (A)]. Below, a two-dimensional (2D) schematic of the TSC:WIPI3 architecture. (C) Schematic showing the domain structure of the TSC components, as well as approximate interfaces and interactions (gray shading) between subunits. CC, coiled coil; HR, HEAT repeat.