| 5214897 |
cip_b |
A |
AG |
Leu87 frameshift 148stop |
MSMEG_5116 |
Uncharacterized protein |
N/A |
Mutation accumulation (MA) |
| 3614832 |
cip_b |
C |
T |
Pro139Leu |
MSMEG_3554 |
N5,N10-methylene-tetrahydromethanopterin reductase |
xidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705] |
| 2208516 |
cip_b |
G |
GA |
Leu282 frameshift 283stop |
MSMEG_2133 |
Uncharacterized protein |
N/A |
| 5861538 |
cip_c |
G |
GC |
Leu168 frameshift |
MSMEG_5792 |
UPF0678 fatty acid-binding protein-like protein MSMEG_5792/MSMEI_5639 |
intracellular transport [GO:0046907] |
| 3415264 |
cip_c |
T |
TC |
Leu206 frameshift 257stop |
MSMEG_3338 |
Oxidoreductase, FAD/FMN-binding |
FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491] |
| 2033295 |
cip_c |
A |
AG |
Leu72 frameshift 258stop |
MSMEG_1954 |
ABC1 family protein |
N/A |
| 1988098 |
cip_c |
A |
AG |
N/A |
Intergenic region |
intergenic |
N/A |
| 1533730 |
inh_b |
C |
CTCG |
Asp201_INSERTION |
MSMEG_1431 |
Cytochrome P450-terp (EC 1.14.-.-) |
heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705] |
| 994997 |
inh_C |
G |
A |
N/A |
intergenic |
|
N/A |
| 5777585 |
inh_C |
C |
T |
Val99Met |
MSMEG_5688 |
Regulatory protein, MarR |
GO:0003700 DNA-binding transcription factor activity; GO:0006355 regulation of DNA-templated transcription |
| 1508883 |
mmc_a |
C |
G |
Ala300Ala (neutral) |
MSMEG_1407 |
N/A |
N/A |
| 4598387 |
mmc_a |
C |
G |
Ala371Arg |
MSMEG_4513 |
Polyketide synthase |
transferase activity, transferring acyl groups [GO:0016746] |
| 6786854 |
mmc_a |
G |
A |
Trp104stop |
MSMEG_6740 |
1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) |
1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310] |
| 5313643 |
mmc_c |
C |
T |
N/A |
intergenic |
N/A |
N/A |
| 1865825 |
mock_b |
G |
GC |
Ala351 frameshift |
MSMEG_1780 |
Natural resistance-associated macrophage protein |
metal ion transmembrane transporter activity; metal ion transport; membrane; |
| 3722101 |
mock_b |
A |
C |
Asn185Thr |
MSMEG_3656 |
ABC transporter, permease/ATP-binding protein |
|
| 58213 |
mock_c |
T |
TC |
N/A |
MSMEG_0037 |
tRNA-Leu |
N/A |
| 4104684 |
mock_c |
T |
C |
Val70Ala |
MSMEG_4033 |
TetR-family protein transcriptional regulator |
GO:0006350, Sequence-specific dna binding transcription factor activity, Regulation of transcription, dna-dependent |
| 5118524 |
mock_c |
C |
CG |
Asp89 frameshift 143stop |
MSMEG_5021 |
Alcohol dehydrogenase, zinc-containing |
Oxidoreductase activity, Zinc ion binding, Oxidation-reduction process |
| 5217666 |
mock_g |
G |
A |
Thr200Thr (neutral) |
MSMEG_5119 |
L-glutamate gamma-semialdehyde dehydrogenase |
Mitochondrial matrix, Oxidation-reduction process, Proline biosynthetic process, 1-pyrroline-5-carboxylate dehydrogenase activity |
| 2970975 |
mock_i |
T |
C |
Arg155Gly |
MSMEG_2908 |
2-Keto-3-deoxy-gluconate kinase |
kinase activity [GO:0016301] |
| 2970982 |
mock_i |
C |
T |
Arg153Glu |
MSMEG_2908 |
2-Keto-3-deoxy-gluconate kinase |
kinase activity [GO:0016301] |
| 3306164 |
mock_i |
G |
A |
Glu1151Glu (neutral) |
MSMEG_3225 |
Ferredoxin-dependent glutamate synthase 1 (EC 1.4.7.1) |
3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamate biosynthetic process [GO:0006537]; glutamine metabolic process [GO:0006541] |
Mutation accumulation (MA) |
| 5805844 |
mock_i |
C |
T |
Val237Val (neutral) |
MSMEG_5721 |
Acetyl-CoA acetyltransferase |
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747] |
| 4987517 |
mock_j |
G |
A |
Leu30Leu (neutral) |
MSMEG_4890 |
Alkyl hydroperoxide reductase AhpD (EC 1.11.1.28) (Alkylhydroperoxidase AhpD) |
alkyl hydroperoxide reductase activity [GO:0008785]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; response to oxidative stress [GO:0006979] |
| 6406902 |
mock_j |
T |
TG |
N/A |
intergenic |
N/A |
N/A |
| 491016 |
mock_k |
C |
T |
N/A |
intergenic |
N/A |
N/A |
| 2287781 |
mock_k |
G |
A |
Gly199Asp |
MSMEG_2207 |
Beta-ketothiolase |
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747] |
| 3438752 |
rif_a |
A |
AC |
Arg17 frameshift 175stop |
MSMEG_3366 |
Isonitrile hydratase, putative |
N/A |
| 5773058 |
rif_a |
C |
T |
Glu67Lys |
MSMEG_5682 |
Uncharacterized protein |
integral component of membrane [GO:0016021] |
| 6220187 |
CIPB0.3 |
G |
T |
Trp53Cys |
MSMEG_6151 |
Alpha/beta hydrolase fold-1 |
epoxide hydrolase activity [GO:0004301] |
Fluctuation assay with CIP treatment |
