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. 2024 Nov 7;15:1478819. doi: 10.3389/fphar.2024.1478819

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Copyright © 2024 Zhu, Liao, Tian, Yu, Xie, Sun, Zhou, Han, Zhao, El-Kassas, Liu, Sun and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The KEGG bubble diagram and Venn diagram of the intersected targets of four diseases associated with estrogen. The abscissa is fold enrichment. (A) Results of the KEGG pathway analysis of the intersected targets of estrogen and obesity. (B) Results of the KEGG pathway analysis of the intersected targets of estrogen and T2DM. (C) Results of the KEGG pathway analysis of the intersected targets of estrogen and AS. (D) Results of the KEGG pathway analysis of the intersected targets of estrogen and NAFLD. (E) The KEGG Venn diagram of the intersected targets of the four diseases and estrogen were obtained, respectively. Abbreviations: AS, atherosclerosis; KEGG, Kyoto encyclopedia of genes and genomes; NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes mellitus.