Table 1.
General characteristics of the participants, lipid profile, and CEC promoted by HDL, over time.
| N = 62 | Baseline | Follow-up post bariatric surgery | Coefficient | p trend | |||
|---|---|---|---|---|---|---|---|
| 1 month | 3 months | 6 months | 12 months | ||||
| Weight (kg) | 117 (18.9) | 105 (17.0)* | 95.0 (16.0)* | 86.6 (16.8)* | 82.0 (16.5)* | −0.13 (−0.14, −0.11) | <0.001 |
| BMI (kg/m2) | 42.6 (5.49) | 38.0 (5.05)* | 34.5 (4.71)* | 31.3 (5.05)* | 29.7 (4.82)* | −0.14 (−0.16, −0.13) | <0.001 |
| Abdominal circumference (cm) | 132 (11.5) | 122 (10.2)* | 116 (10.1)* | 110 (13.3)* | 105 (13.3)* | −0.14 (0.15, −0.12) | <0.001 |
| Glucose (mg/dl) | 101 (21.0) | 90.8 (15.7) | 87.2 (6.59)* | 88.2 (7.39)* | 89.3 (9.24)* | −0.04 (−0.06, −0.02) | <0.001 |
| Total cholesterol (mg/dl) | 176 (28.3) | 147 (41.7)* | 162 (36.1)* | 162 (33.5)* | 161 (27.0)* | −0.01 (−0.03, 0.01) | 0.174 |
| LDL cholesterol (mg/dl) | 115 (25.0) | 95.9 (33.6)* | 104 (28.9) | 99.8 (28.1)* | 95.0 (24.3)* | −0.04 (−0.06, −0.02) | <0.001 |
| HDL cholesterol (mg/dl) | 46.9 (12.9) | 38.9 (11.0)* | 45.6 (11.8)* | 51.7 (11.8)* | 60.8 (14.2)* | 0.10 (0.09, 0.12) | <0.001 |
| Remnant cholesterol (mg/dl) | 14.0 (7.53) | 16.4 (7.17)* | 14.2 (8.20) | 10.5 (5.87)* | 7.16 (5.67)* | −0.09 (−0.12, −0.07) | <0.001 |
| Triglycerides (mg/dl) | 105 (46.8) | 98.4 (39.2) | 90.9 (38.3) | 79.1 (27.7)* | 73.5 (30.1)* | −0.07 (−0.09, −0.06) | <0.001 |
| HDL Cholesterol efflux capacity (%) | 0.98 (0.15) | 0.97 (0.14)** | 1.03 (0.11) | 1.00 (0.14) | 1.04 (0.13)** | 0.04 (0.01, 0.07) | 0.010 |
| HDL VCAM secretion (ng/ml) | 6.83 (2.13) | 7.02 (1.87) | 6.71 (2.18) | 7.14 (2.05) | 7.61 (2.39) | 0.03 (0.01, 0.03) | 0.013 |
BMI, body mass index; LDL, low-density lipoprotein; HDL, high-density lipoprotein.
Baseline and follow-up values are presented as mean (SD). Model adjusted by age, sex, type of intervention, and treatment of dyslipidemia.
*
p-value < 0.05.
**
Borderline p-value < 0.01.