Fig. 6. Extending the HNOCA by means of projection of extra datasets.

a, Schematic of projecting further scRNA-seq data by the community to extend the HNOCA. b, UMAP shows the dataset composition of the current extended HNOCA. c, UMAP shows the projected cell type annotation of cells in the five extended datasets. NE, neuroepithelium; NC-D, neural crest derivatives; MC, mesenchymal cell; EC, endothelial cell. d, Dot plot shows the expression of selected cell type and regional markers across projected cell types in the extended HNOCA datasets. e, Dot plot shows cell type composition and average similarity to the matched HNOCA metacells of the extended datasets. f, Schematic shows the analytical pipelines and varied interfaces to facilitate analysing scRNA-seq data of neural organoids for the community.