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Circle diagrams of the discovery sample in the forward MR analysis. The complete results of the forward MR analysis, showing the causal effects of plasma metabolites on ADs. (A) IBD, (B) MS, (C) RA, (D) T1D. Five statistical methods, respectively, IVW, MR Egger, Weighted median, Weighted mode, and Simple mode, are represented by five circles from inner to outer.
