Table 1.

Overview of the fold change of the top 25 substrate sequences during the three incubation rounds of the Enrich2 CLiPS Library with PANC-1 lysates.

	Start	PDAC-1		PDAC-2		PDAC-3
Sequence	Ratio	Ratio	Fold change	Ratio	Fold change	Ratio	Fold change
CLIQFF	2.22E−08	4.12E−06	185.83	1.05E−05	472.44	8.96E−05	4038.53
NQCYVS	2.22E−08	2.42E−06	108.84	6.76E−06	304.61	5.79E−05	2608.85
FLIFLI	6.66E−08	1.07E−05	160.61	3.81E−05	572.57	1.69E−04	2544.51
FWGLVW	2.22E−08	1.12E−06	50.44	2.80E−06	126.26	4.65E−05	2096.53
FLFNAC	1.55E−07	8.63E−06	55.56	2.83E−05	182.11	3.01E−04	1935.79
VQLMVI	6.66E−08	3.24E−06	48.67	9.76E−06	146.61	1.18E−04	1769.46
QDDEFL	1.55E−07	5.19E−06	33.37	2.53E−05	162.57	2.64E−04	1696.07
FHLDLN	2.22E−08	9.43E−07	42.48	2.93E−06	132.05	3.61E−05	1626.91
PVLLVG	2.44E−07	1.01E−05	41.51	2.19E−05	89.72	3.66E−04	1499.44
SGHHHS	4.44E−08	5.92E−06	133.40	2.39E−05	538.47	6.31E−05	1421.21
CSFAVS	1.09E−06	7.93E−06	7.29	7.27E−05	66.80	1.28E−03	1180.51
IYACSS	2.00E−07	5.54E−06	27.73	1.38E−05	69.27	2.17E−04	1084.92
QCCLYL	8.66E−07	1.16E−05	13.41	5.11E−05	58.98	9.26E−04	1069.43
FFLFSS	2.22E−08	6.84E−06	307.95	1.24E−05	558.72	2.35E−05	1058.15
LIFLRN	1.33E−07	3.15E−06	23.67	8.56E−06	64.27	1.26E−04	944.42
FLIVHS	2.66E−07	9.43E−06	35.40	3.78E−05	142.09	2.22E−04	832.63
CTVLHD	1.78E−07	3.39E−06	19.08	1.03E−05	58.20	1.44E−04	813.46
LCMLCY	1.78E−07	4.63E−06	26.05	1.19E−05	67.01	1.40E−04	789.42
PPRPMF	8.88E−08	3.95E−06	44.47	1.22E−05	137.58	6.98E−05	786.46
PPELLI	2.22E−08	5.01E−07	22.57	1.51E−06	67.87	1.73E−05	777.29
IFWRMR	4.44E−07	7.98E−06	17.99	2.28E−05	51.45	3.09E−04	696.25
FLFLFL	2.22E−08	5.13E−06	230.96	8.57E−06	386.16	1.52E−05	686.97
CALFSI	2.22E−08	1.30E−06	58.40	3.56E−06	160.46	1.52E−05	686.26
CTVLND	1.78E−07	1.41E−06	7.96	6.75E−06	38.01	1.19E−04	670.16
SCRWSE	1.55E−07	6.54E−06	42.10	1.79E−05	115.37	1.04E−04	668.67

The start ratio is determined by normalizing the reads per substrate to the total amount of reads in a given sample.