Figure 8. Zonated enrichment of 3β-NBD-TCA in a subpopulation of renal proximal TEC in Oatp^KO mice injected with Myrcludex B. A. Stills before and 30 min after injection of 3β-NBD-TCA. B. Co-immunostaining of the kidneys of Oatp^KO mice for aquaporin1 (AQP1), thiazide sensitive NaCl cotransporter (TSC) and mAsbt. The dark mAsbt-associated staining is seen on the luminal membrane of a subpopulation of AQP1 positive TEC. The data are from a representative mouse out of 3 mice per condition.