Figure 9. Inhibition of mAsbt by AS0369 blocks 3β-NBD-TCA enrichment in renal proximal TEC of OatpKO mice treated with Myrcludex B. A. Stills of 2-photon videos. B. Overview image recorded 30 min after 3β-NBD-TCA administration. C. Quantification of 3β-NBD-TCA-associated fluorescence in renal peritubular capillaries, tubular lumen, and tubular epithelial cells. Red: TMRE; green: 3β-NBD-TCA; blue: Hoechst 33258. The data corresponds to supplementary video 7. The data are from a representative mouse out of 3 mice.
