Table 3.
Non-module membered tyrosine metabolism pathway genes with significant Pearson correlation to melanin concentration.
| Gene Name | Gene description | Orthogroup | Pearson correlation | P-value |
|---|---|---|---|---|
| ADH1A | Alcohol dehydrogenase 1A (class I), alpha polypeptide | OG0004227 | −0.3868996 | 0.00602846 |
| ADH1B | Alcohol dehydrogenase 1B (class I), beta | OG0003914 | −0.4565233 | 0.00097698 |
| ADH1C | Alcohol dehydrogenase 1C (class I), gamma polypeptide | OG0005371 | −0.3808345 | 0.0069426 |
| ADH4 | Alcohol dehydrogenase 4 (class II), pi polypeptide | OG0010654 | −0.2903729 | 0.04297246 |
| ADH5 | Alcohol dehydrogenase 5 (class III), chi | OG0007001 | 0.3875348 | 0.00593908 |
| ALDH1A3 | Aldehyde dehydrogenase 1 family member A3 | OG0004406 | 0.29366773 | 0.0405594 |
| ALDH3A1 | Aldehyde dehydrogenase 3 family member A1 | OG0002905 | 0.32896483 | 0.02100162 |
| ALDH3B1 | Aldehyde dehydrogenase 3 family member B1 | OG0008949 | 0.30488644 | 0.03316219 |
| COMT | Catechol-O-methyltransferase | OG0001002 | 0.45817774 | 0.00093114 |
| GOT2 | Glutamic-oxaloacetic transaminase 2 | OG0002600 | 0.39805816 | 0.00461761 |
| MAOA | Monoamine oxidase A | OG0004777 | −0.42236 | 0.00250248 |
In this table, genes part of the tyrosine metabolism pathway that were not associated with a module within the pathway were identified as correlated to melanin concentration. The gene name, gene description, the corresponding orthogroup number, and the Pearson correlation and P-value (P < 0.05) are reported.