Fig. 3.

Fcnb deficiency exacerbated pulmonary fibrosis in BLM-treated mice. (A) Work flow of murine models. (B) The body weight change during BLM treatment was monitored (n = 6–12 per group). (C) Survival studies were conducted in the BLM lung fibrosis model (n = 6–12 per group). (D) The lungs from WT and Fcnb^−/− mice were stained with Masson’s trichrome (n = 6–10 per group). (E) Histological analysis of the severity of lung fibrosis in mice after BLM induction (n = 6–10 per group). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 by one-way ANOVA (D), two-way ANOVA (A) or Kaplan-Meier (B). Fcnb, ficolin-B