Fig. 9.

FCN1 interacted with TGF-β1 in pulmonary fibrosis. (A) Co‑immunoprecipitation analysis of TGF-β1 and FCN1 in serum of IPF patients. (B) Representative results for co-immunostaining of FCN1 and TGF-β1 in lung sections derived from lung explant material from an IPF patient. The nuclei were stained DAPI, and the images were taken under original magnification ×400. (C-D) Western blot analysis of FCN1 expression in A549 cells after TGF-β1 induction (n = 3 per group). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 by one-way ANOVA (D). FCN1, ficolin-1; Fcnb, ficolin-B