Table 3. Cox proportional-hazards analysis of factors associated with mortality in SSc.

	HR (95% CI)	P
General features
Age at diagnosis (per 1 year)	1.07 (1.06 to 1.09)	<0.0001
Male sex	1.49 (0.93 to 2.4)	0.10
Clinical features
dcSSc subtype	1.2 (0.73 to 1.97)	0.48
PAH	4.46 (2.99 to 6.67)	<0.0001
ILD	0.87 (0.56 to 1.37)	0.56
SRC	3.56 (1.78 to 7.1)	0.0003
Antibody
ATA	1.9 (1.01 to 3.58)	0.05
ACA	0.77 (0.4 to 1.48)	0.43
Anti-RNAPIII	2.35(1.12to4.93)	0.02
Anti-U1RNP	0.44 (0.06 to 3.39)	0.43
Anti-U3RNP	2.63 (0.95 to 7.28)	0.06
Anti-Pm/Scl	–	–
Anti-Ku	–	–
Anti-Th/To	–	–
Anti-NOR90	–	–

Statistically significant values are put in bold.

ACA, anti-centromere antibody; anti-RNAPIII, anti RNA polymerase III antibodyATA, anti-topoisomerase I antibody; dcSSc, diffuse systemic sclerosis; PAH, pulmonary arterial hypertension; SRC, scleroderma renal crisisSScsystemic sclerosis