TABLE 1.
Meta-analysis of genome-wide association study summary statistics identifies six independent genomic variants which are associated with Clostridioides difficile infectiona
| rsID | Chr | BP (build:hg19) |
EA | OA | EA frequency | Beta | Standard error | P value | Function | Gene |
|---|---|---|---|---|---|---|---|---|---|---|
| rs3134745 | 6 | 31,242,762 | t | c | 0.328 | −0.160 | 0.029 | 4.27E−08 | Intergenic | HLA-C;LINC02571 |
| rs10927954 | 1 | 14,245,266 | c | g | 0.097 | 0.185 | 0.038 | 8.72E−07 | Intergenic | PRDM2;KAZN-AS1 |
| rs12458428 | 18 | 71,331,397 | a | c | 0.328 | 0.124 | 0.027 | 3.23E−06 | Intergenic | LINC02582;FBXO15 |
| rs11707141 | 3 | 108,487,582 | a | g | 0.720 | −0.124 | 0.027 | 5.22E−06 | Intergenic | RETNLB;TRAT1 |
| rs1182870 | 1 | 208,971,963 | t | c | 0.878 | −0.179 | 0.039 | 5.98E−06 | Intergenic | LINC01717;LINC01774 |
| rs10031490 | 4 | 109,771,479 | a | g | 0.861 | −0.171 | 0.038 | 8.54E−06 | Intronic | COL25A1 |
a
BP, base position; Chr, chromosome; EA, effect allele; OA, other allele.