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. 2024 Nov 21;22:1050. doi: 10.1186/s12967-024-05871-8

Fig. 6.

Fig. 6

MiR-195-5p regulates ECM and myofibroblast transdifferentiation of TGF-β-treated ESCs by targeting the YAP-Smad7 signaling pathway. A COIP detection of the targeting relationship between YAP and Smad7. BF RT-PCR and Western blot analysis of YAP and Smad7 expression in uterine tissue after miR-195-5p mimic treatment. GI Immunofluorescence analysis of YAP and Smad7 expression in uterine tissue after miR-195-5p mimic treatment. JM Western blot analysis of YAP and Smad7 expression in uterine tissue after miR-195-5p mimic treatment and Smad7 knockdown. (ns = not significant, *P < 0.05, **P < 0.01, ****P < 0.001)