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. 2024 Nov 28;30(44):4725–4737. doi: 10.3748/wjg.v30.i44.4725

Table 2.

Univariate logistic regression analysis of the predictors of hepatitis B surface antigen recurrence

Characteristics
OR
95%CI
P value
Age (years) 0.962 (0.916-1.012) 0.133
Gender 1.692 (0.588-4.870) 0.329
Family history of HBV infection 0.655 (0.227-1.890) 0.434
Characteristics at the initiation of peg-IFN-α
HBsAg level, IU/mL 1.000 (1.000-1.000) 0.398
HBsAb negative 0.933 (0.107-8.130) 0.950
HBV DNA positive 0.514 (0.176-1.506) 0.225
HBeAg positive 1.448 (0.302-6.934) 0.643
Peg-IFN-α-2a 1.624 (0.558-4.730) 0.374
Peg-IFN-α monotherapy 0.588 (0.224-1.546) 0.282
Treatment time of peg-IFN-α (weeks) 1.014 (0.992-1.035) 0.217
Total duration of peg-IFN-α (weeks) 0.999 (0.975-1.024) 0.9570
Consolidation time < 12 weeks 25.636 (7.039-93.356) < 0.001
Characteristics at the cessation of peg-IFN-α
Without HBsAg seroconversion 5.252 (1.684-16.376) 0.004
HBsAb, mIU/mL 0.952 (0.914-0.992) 0.018
HBsAb < 35.3 mIU/mL 9.705 (2.098-44.883) 0.004
HBsAb disappeared during the follow-up 14.500 (1.513-138.972) 0.020
ALT level at baseline, IU/L 1.011 (1.001-1.021) 0.127
FibroScan values at baseline (kPa) 1.314 (0.791-2.183) 0.292

HBV: Hepatitis B virus; Peg-IFN-α: Peginterferon alpha; HBsAg: Hepatitis B surface antigen; HBsAb: Hepatitis B surface antibody; ALT: Alanine aminotransferase; OR: Odds ratio.