Table 1.
Comparison of demographic, health measurements, and polygenic risk score values overall and among non-Hispanic Whites 40 or older without diabetes, with and without any missing values in the Michigan Genomics Initiative.
| Overall | Incomplete observations | Complete observations | Non-missing PRS | ||
|---|---|---|---|---|---|
| Characteristic | N = 42,999a | N = 17,479a | N = 25,520a | p-valueb | N = 30,942a |
| Age | 63.5 (12.5) | 62.6 (12.4) | 64.1 (12.5) | <0.001 | 63.7 (12.5) |
| Female | 53.8 (23,145) | 54.6 (9,547) | 53.3 (13,598) | 0.006 | 53.4 (16,509) |
| Smoking status (ever) | 49.4 (18,187) | 46.5 (5,255) | 50.7 (12,932) | <0.001 | 50.1 (14,320) |
| Missing | 6,178 | 6,178 | 0 | 2348 | |
| BMI | 29.1 (6.0) | 29.1 (6.0) | 29.0 (5.9) | 0. 3 | 29.0 (5.9) |
| Missing | 236 | 236 | 0 | 138 | |
| Glucose | 99.5 (14.2) | 99.5 (14.7) | 99.5 (14.0) | 0.023 | 99.8 (14.3) |
| Missing | 4,836 | 4,836 | 0 | 3560 | |
| BMI PRSc | 0.000 (1.000) | 0.004 (1.021) | −0.001 (0.996) | 0. 6 | 0.000 (1.000) |
| Missing | 12,057 | 12,057 | 0 | 0 | |
| Glucose PRSc | 0.000 (1.000) | 0.013 (0.989) | −0.003 (1.002) | 0. 4 | 0.000 (1.000) |
| Missing | 12,057 | 12,057 | 0 | 0 |
a
continuous: mean (SD); dichotomous: % (n)
b
Wilcoxon rank sum test; Pearson’s Chi-squared test
c
PRS were mean standardized
Abbreviations: BMI, body mass index; PRS, polygenic risk score