Table 2.
Comparison of demographic, health measurements, and polygenic risk score values overall and among non-Hispanic Blacks 40 or older without diabetes, with and without any missing values in the Michigan Genomics Initiative.
| Overall | Incomplete observations | Complete observations | Non-missing PRS | ||
|---|---|---|---|---|---|
| Characteristic | N = 2,297a | N = 1,057a | N = 1,240a | p-valueb | N = 1,437a |
| Age | 57.8 (11.4) | 57.3 (11.2) | 58.2 (11.6) | 0.069 | 57.7 (11.6) |
| Female | 63.3 (1,454) | 63.2 (668) | 63.4 (786) | >0.9 | 63.3 (910) |
| Smoking status (ever) | 42.6 (847) | 39.2 (293) | 44.7 (554) | 0.017 | 44.3 (597) |
| Missing | 310 | 310 | 0 | 88 | |
| BMI | 30.8 (6.4) | 30.6 (6.3) | 31.0 (6.5) | 0. 2 | 31.0 (6.5) |
| Missing | 26 | 26 | 0 | 8 | |
| Glucose | 95.1 (12.5) | 94.0 (12.6) | 95.8 (12.4) | <0.001 | 95.8 (12.4) |
| Missing | 160 | 160 | 0 | 116 | |
| BMI PRSc | 0.000 (1.000) | −0.006 (0.977) | 0.001 (1.004) | 0. 8 | 0.000 (1.000) |
| Missing | 860 | 860 | 0 | 0 | |
| Glucose PRSc | 0.000 (1.000) | 0.158 (1.064) | −0.025 (0.988) | 0.061 | 0.000 (1.000) |
| Missing | 860 | 860 | 0 | 0 |
a
continuous: mean (SD); dichotomous: % (n)
b
Wilcoxon rank sum test; Pearson’s Chi-squared test
c
PRS were mean standardized
Abbreviations: BMI, body mass index; PRS, polygenic risk score