Table 2. Comparison of study groups based on patients’ variables before and after administration of study drugs.
| Variables | Group-1 | Group-2 | ||||||
|---|---|---|---|---|---|---|---|---|
| Pre | Post | Pre-Post | P-value | Pre | Post | Pre-Post | P-value | |
| Mean ± SD | Mean ± SD | % Diff | Mean ± SD | Mean ± SD | %Diff | |||
| Weight (Kg) | 75.1 ± 14.4 | 73.8 ± 13.9 | 1.74% | <0.001* | 73.0 ± 14.9 | 71.8 ± 14.8 | 1.65% | <0.001* |
| Body Mass Index (BMI) | 28.0 ± 5.1 | 27.5 ± 5.1 | 1.08% | <0.001* | 27.3 ± 6.3 | 27.0 ± 6.2 | 1.10% | 0.131 |
| HbA1c | 10.3 ± 1.7 | 9.1 ± 1.6 | 12.37% | <0.001* | 9.9 ± 1.6 | 9.0 ± 1.7 | 9.52% | 0.002* |
| Random Blood Sugar (RBS) | 282.6 ± 77.2 | 248.6 ± 77.3 | 12.80% | <0.001* | 280.0 ± 79.7 | 258.3 ± 85.6 | 8.06% | 0.013* |
| Fasting Blood Sugar (FBS) | 181.4 ± 58.3 | 160.3 ± 52.3 | 12.35% | 0.006* | 190.8 ± 56.7 | 169.8 ± 58.6 | 11.64% | 0.005* |
| Triglycerides | 191.2 ± 36.1 | 184.9 ± 37.7 | 3.35% | 0.151 | 227.5 ± 106 | 224.2 ± 110.9 | 1.46% | 0.83 |
| Cholesterol | 188.0 ± 25.0 | 181.3 ± 24.9 | 3.62% | 0.023* | 181.3 ± 42.4 | 182.1 ± 40.2 | -0.44% | 0.896 |
| Low-Density Lipoprotein (LDL) | 110.8 ± 20.3 | 104.0 ± 23 | 6.33% | 0.003* | 103.5 ± 29.4 | 108.0 ± 26.3 | -4.25% | 0.395 |
| High-Density Lipoprotein (HDL) | 43.7 ± 2.8 | 44.6 ± 3.7 | -2.03% | 0.149 | 43.3 ± 8.8 | 42.8 ± 4 | 1.16% | 0.732 |
| Serum Creatinine | 0.9 ± 0.2 | 0.8 ± 0.2 | 11.76% | 0.878 | 1.3 ± 1.1 | 1.2 ± 1.2 | 8.0% | 0.303 |
| Urea | 32.0 ± 8 | 30.7 ± 6.4 | 4.14% | 0.34 | 38.9 ± 20.2 | 39.3 ± 24 | -1.02% | 0.885 |
Pair t-test was used, * p-value <0.05 was statistically significant