Table 3. Multivariate logistic regression analysis of dietary niacin for risk of COPD.
| Variable | n. event (%) | Crude model | Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | ||
| Quartile | |||||||||
| Q1 (≤16.08) | 254 (14.2) | 1(Ref) | 1(Ref) | 1(Ref) | 1(Ref) | ||||
| Q2(16.09–21.84) | 221 (12.3) | 0.85 (0.7~1.03) | 0.106 | 0.85 (0.7~1.03) | 0.102 | 0.97 (0.78~1.19) | 0.742 | 0.96 (0.77~1.19) | 0.706 |
| Q3(21.85–28.97) | 189 (10.5) | 0.71(0.58~0.8) | 0.001 | 0.73 (0.59~0.9) | 0.003 | 0.79 (0.63~0.99) | 0.041 | 0.78 (0.62~0.99) | 0.038 |
| Q4 (≥28.98) | 170 (9.5) | 0.63(0.52~0.7) | <0.001 | 0.72 (0.57~0.9) | 0.004 | 0.76 (0.58~1.00) | 0.05 | 0.76 (0.57~1.00) | 0.047 |
| P for trend | <0.001 | 0.001 | 0.018 | 0.017 | |||||
Abbreviations: COPD, chronic obstructive pulmonary disease; Q, quartiles; OR, odds ratio; CI, confidence interval; Ref: reference.
The crude model was not adjusted for covariates.
Model I was adjusted for sex, age, race/ethnicity.
Model2 was adjusted for sex, age, race/ethnicity, family income, physical activity, smoking status, education level, marital status, body mass index, serum cotinine, total energy.
Model 3 was adjusted for sex, age, race/ethnicity, family income, physical activity, smoking status, education level, marital status, body mass index, serum cotinine, total energy, hypertension, high cholesterol, diabetes, coronary heart disease, stroke, cancer.