Table 2. BMI Status Prior to SARS-CoV-2 Infection and Risk of PASCa.
| Outcome by BMI status | Incident vs total COVID-19 cases, No./total No. (%)b | RR (95% CI) | P value for trend |
|---|---|---|---|
| PASCc | |||
| Healthy weight | 514/68 918 (0.7) | 1 [Reference] | .001 |
| Overweight | 137/17 605 (0.8) | 1.05 (0.87-1.26) | |
| Obesity | 199/25 372 (0.8) | 1.25 (1.06-1.48) | |
| Severe obesity | 552/60 241 (0.9) | 1.42 (1.25-1.61) | |
| PASC symptoms and conditions | |||
| Any occurrences | |||
| Healthy weight | 28 674/68 918 (41.6) | 1 [Reference] | <.001 |
| Overweight | 7637/17 605 (43.4) | 1.03 (0.98-1.08) | |
| Obesity | 11 081/25 372 (43.7) | 1.11 (1.06-1.15) | |
| Severe obesity | 26 925/60 241 (44.7) | 1.17 (1.14-1.21) | |
| Total occurrences, median (IQR) | |||
| Healthy weight | 0 (0-2) | 1 [Reference] | <.001 |
| Overweight | 0 (0-2) | 1.05 (1.00-1.11) | |
| Obesity | 0 (0-2) | 1.14 (1.09-1.19) | |
| Severe obesity | 0 (0-2) | 1.18 (1.14-1.22) |
Abbreviations: BMI, body mass index; PASC, post-acute sequelae of SARS-CoV-2 infection; RR, relative risk.
Adjusted for age at BMI assessment and at cohort entry (continuous), sex, race and ethnicity, pediatric medical complexity algorithm index, predominant variant, acute COVID-19 severity, numbers of emergency department visits, outpatient department visits, inpatient department visits, medications or prescriptions, and negative COVID-19 tests.
Incident refers to the count of participants who developed the outcome we were interested in (ie, PASC or PASC symptoms and conditions); total COVID-19 cases refers to the count of the participants in the corresponding group; and the value in the parentheses refers to the percentage of the groups who developed the outcome.
International Statistical Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code U09.9.