Table 3. Change in VASI From Baseline by Global Impression of Change at Week 24.

Scale	Outcome measure	Improvement		No change		Worsened		Overall F valuea	P value for pairwise comparisonsb
		No.	LS mean (SE) [95% CI]	No.	LS mean (SE) [95% CI]	No.	LS mean (SE) [95% CI]
T-VASI	PhGIC-V	76	−5.7 (0.8) [−7.4 to −4.0]	68	−0.8 (0.8) [−2.4 to 0.9]	13	0.9 (1.6) [−2.3 to 4.1]	5.6	1: <.001; 2: <.001; 3: .59
	PaGIC-V	74	−6.0 (0.8) [−7.6 to −4.3]	60	−0.7 (0.8) [−2.3 to 1.0]	26	−0.8 (1.2) [−3.2 to 1.6]	5.7	1: <.001; 2: <.001; 3: >.99
F-VASI	PhGIC-V	76	−0.5 (0.1) [−0.6 to −0.4]	68	−0.1 (0.1) [−0.2 to 0.03]	13	−0.01 (0.11) [−0.2 to 0.2]	8.3	1: <.001; 2: ≤.0001; 3: .78
	PaGIC-V	74	−0.5 (0.1) [−0.5 to −0.3]	60	−0.1 (0.1) [−0.3 to −0.02]	26	−0.03 (0.08) [−0.2 to 0.1]	6.2	1: <.001; 2: <.001; 3: .47

Abbreviations: F-VASI, Facial Vitiligo Area Scoring Index; LS, least-squares; PaGIC-V, Patient’s Global Impression of Change-Vitiligo; PhGIC-V, Physician’s Global Impression of Change-Vitiligo; SE, standard error; PaGVA-T, Total-Patient Global Vitiligo Assessment; T-VASI, Total Vitiligo Area Scoring Index.

^a General linear model controlling for covariates (T-VASI baseline score, age, sex, skin tone).

^b Pairwise comparisons between LS means were performed using Scheffe test adjusting for multiple comparisons: 1, improvement vs no change, 2, improvement vs worsened; and 3, no change vs worsened.