Table 2. Associations Between Dietary Pattern Scores and Overall Survival.
Dietary pattern score | All participants (n = 483) | HGSOC (n = 325) | ||||||
---|---|---|---|---|---|---|---|---|
HEI-2020a | AHEI-2010a | HEI-2020a | AHEI-2010a | |||||
Deaths/participants, No. | HR (95% CI)b | Deaths/participants, No. | HR (95% CI)b | Deaths/participants, No. | HR (95% CI)b | Deaths/participants, No. | HR (95% CI)b | |
Quartilec | ||||||||
1 | 80/121 | 1 [Reference] | 83/121 | 1 [Reference] | 63/75 | 1 [Reference] | 68/82 | 1 [Reference] |
2 | 77/121 | 0.82 (0.59-1.12) | 74/121 | 0.80 (0.58-1.10) | 56/83 | 0.63 (0.44-0.92) | 53/82 | 0.62 (0.43-0.89) |
3 | 78/121 | 0.87 (0.63-1.20) | 83/121 | 1.02 (0.75-1.40) | 56/81 | 0.67 (0.46-0.97) | 64/85 | 0.92 (0.65-1.31) |
4 | 75/120 | 0.78 (0.56-1.08) | 70/120 | 0.83 (0.89-1.16) | 58/86 | 0.63 (0.44-0.91) | 48/76 | 0.67 (0.45-0.98) |
P value for trend | NA | .19 | NA | .52 | NA | .03 | NA | .17 |
Per 10-point increase | NA | 0.93 (0.82-1.05) | NA | 0.95 (0.85-1.07) | NA | 0.86 (0.75-1.00) | NA | 0.89 (0.77-1.01) |
Abbreviations: AHEI-2010, Alternative Healthy Eating Index-2010; HGSOC, high-grade serous ovarian cancer; HEI-2020, Healthy Eating Index-2020; HR, hazard ratio; NA, not applicable.
Score ranges were 0 to 100 for HEI-2020 and 0 to 110 for AHEI-2010.
The Cox proportional hazard model was adjusted for age (years), education (≤high school graduate, some college, ≥college graduate), annual household income (<$25 000, ≥$25 000, or unknown), physical activity in the year before diagnosis (yes or no), smoking status (never, current, or former smoker), study site (Southwest, Southeast, or North), and histotype (HGSOC or other). In the analysis among patients with HGSOC, histotype was not adjusted.
Quartile 1 and Q4 indicate low and high adherence to dietary guidelines, respectively.