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Median (interquartile range) serum creatinine change in participants with (A) acute kidney injury (AKI) or (B) chronic kidney disease (CKD). Reference line represents no change from baseline (ie, y = 0). Kidney disease status categories are mutually exclusive; for participants without dialysis-treated chronic kidney failure at screening, the status was AKI in participants with ongoing AKI and CKD in those with a history of CKD.
