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. 2024 Nov 8;12:1420330. doi: 10.3389/fbioe.2024.1420330

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Copyright © 2024 Snider, Vega, Nessen, Hernandez Torres, Salazar, Berard and Salinas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Physiological data trends during the second resuscitation event (blue), where the crystalloid infusate was used during the entire resuscitation and maintenance window to reach and maintain the target MAP. Results are compared against the first resuscitation event (red) for (A) average MAP trends (first resuscitation n = 12; second resuscitation n = 9), (B) central venous pressure (n = 8 for each), (C) mixed venous saturation (n = 8 for each), (D) cardiac output (n = 8 for each), and (E) stroke volume variability (n = 8 for each). Standard deviation is shown as the shaded region for both resuscitation events.