Table 1.
Correlation between clinical and pathological characteristics and Tim-3 expression.
| Characteristics | Low Expression (n=52) | High Expression (n=50) | Z/x2 | P-value |
|---|---|---|---|---|
| Gender | 2.152 | 0.142 | ||
| Male | 40 | 44 | ||
| Female | 12 | 6 | ||
| Age | 54.810 ± 14.059 | 58.740 ± 13.638 | -1.433 | 0.155* |
| BMI | 23.204 ± 3.251 | 22.388 ± 3.284 | 1.261 | 0.210* |
| Family history | 0.161 | |||
| Negative | 45 | 48 | ||
| Positive | 7 | 2 | ||
| Viral hepatitis | 0.314 | 0.575 | ||
| Negative | 17 | 19 | ||
| Positive | 35 | 31 | ||
| Cirrhosis | 0.810 | 0.368 | ||
| Negative | 12 | 8 | ||
| Positive | 40 | 42 | ||
| Tumor number | 0.005 | 0.942 | ||
| 1 | 46 | 44 | ||
| ≤3 | 6 | 6 | ||
| Tumor size | 3.175 | 0.075 | ||
| <5 | 36 | 26 | ||
| ≥5 | 16 | 24 | ||
| AFP (ng/mL) | 0.118 | 0.731 | ||
| <200 | 39 | 36 | ||
| ≥200 | 13 | 14 | ||
| Child-Pugh score | 2.761 | 0.097 | ||
| A | 41 | 32 | ||
| B | 11 | 18 | ||
| BCLC score | -2.352 | 0.019 | ||
| 0 | 24 | 10 | ||
| A | 23 | 35 | ||
| B | 5 | 5 | ||
| TNM stage(I/II,III) | 0.942 | 0.332 | ||
| I | 34 | 28 | ||
| II,III | 18 | 22 | ||
| Pathological grading | 1.095 | 0.613 | ||
| Well | 2 | 4 | ||
| Moderately | 47 | 42 | ||
| Poorly | 3 | 4 | ||
| MVI | 0.343 | 0.558 | ||
| Negative | 42 | 38 | ||
| Positive | 10 | 12 | ||
| Satellite nodules | 0.211 | 0.646 | ||
| Negative | 43 | 43 | ||
| Positive | 9 | 7 | ||
| Histological morphology | 35.751 | 0.000 | ||
| Trabecular-micro | 36 | 11 | ||
| Trabecular-macro | 4 | 20 | ||
| Pseudoglandular | 10 | 5 | ||
| Compact types | 2 | 14 | ||
| ALT | 29.850(21.325-46.050) | 41.950(29.308-58.568) | -1.951 | 0.051 |
| AST | 30.150(24.575-40.125) | 44.700(27.575-72.950) | -2.775 | 0.006 |
Data marked with an asterisk (*) were analyzed using the student’s T-test.