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. 2024 Nov 8;14:1429309. doi: 10.3389/fcimb.2024.1429309

Table 3.

Clinical and hospital characteristics of primary and postprimary dengue patients with DENV/CoV subsequent infection.

Characteristics Dengue primary (n = 9) Dengue postprimary (n = 15) p-value
Patients N (%) Patients N (%)
Sex 1.000
 Female 8 3 (37.5) 15 5 (33.33)
 Male 8 5 (62.5) 15 10 (66.67)
Age, mean [median] 7 49.29 [15.50] 15 63.73 [9.05] 0.056
Age group (years) 0.251
 21–40 9 1 (11.11) 15 0 (0)
 41–60 9 5 (55.56) 15 6 (40)
 > 60 9 3 (33.33) 15 9 (60)
Race 1.000
 White 8 8 (100) 15 14 (93.33)
 Black 8 0 (0) 15 1 (6.67)
Education level 0.078
 No school
 Incomplete basic school 8 4 (50) 13 7 (53.85)
 Complete basic school 8 4 (50) 13 1 (7.69)
 High school 8 0 (0) 13 4 (30.77)
 Graduated 8 0 (0) 13 1 (7.69)
Days of symptom onset 0.643
 0–7 9 1 (11.11) 15 1 (6.67)
 8–14 9 1 (11.11) 15 4 (26.67)
 > 14 9 7 (77.78) 15 10 (66.67)
Days of symptoms, mean [median] 22 19.50 [6.50] 331 20.42 [9.87] 0.585
Initial symptoms
 Fever 8 7 (87.5) 15 5 (33.33) 0.027
 Cough 8 7 (87.5) 15 13 (86.67) 1.000
 Sore throat 8 0 (0) 15 1 (6.67) 1.000
 Dyspnea 8 8 (100) 15 13 (86.67) 0.526
 Respiratory distress 8 4 (50) 15 10 (66.67) 0.657
 Low saturation 8 8 (100) 15 15 (100) NA
 Diarrhea 8 0 (0) 15 2 (13.33) 0.526
 Abdominal pain 8 0 (0) 15 0 (0) NA
 Vomit 8 0 (0) 15 2 (13.33) 0.526
 Fatigue 8 4 (50) 15 7 (46.67) 1.000
 Altered taste 8 0 (0) 15 0 (0) NA
 Anosmia 8 0 (0) 15 0 (0) NA
Severity
 Hospitalization in ICU 8 7 (87.5) 15 15 (100) 0.348
Mechanical ventilation
 Yes, invasive 8 7 (87.5) 15 13 (86.67) 0.230
 Yes, noninvasive 8 0 (0) 15 2 (13.33)
 No 8 1 (12.5) 15 0 (0)
Hospitalization outcome 0.361
 Discharge 8 5 (62.5) 15 6 (40)
 Death 8 2 (25) 15 9 (60)
Hospital admitted, mean [median] 7 2.40 [3.54] 15 4.00 [7.07] 0.591
ICU admitted, mean [median] 7 13.93 [5.81] 15 20.29 [9.53] 0.190

NA, not available.

Values are expressed as medians.

p values > 0.05 indicate a good model fit.