Fig. 6.

Residual flexibility throughout the MD simulation. (A) RMSF of backbone atoms throughout the trajectories. (B) Heatmap representing △RMSF of G17A, W19C, F136S, and C119R relative to WT. (C) Structural representation of the strong residual cross-correlation in all the systems. Red and blue lines denote the most correlated and anti-correlated interactions between two residues. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)