Fig. 1. Scalable processing compatibility.

Preferential properties of 2-methyltetrahydrofuran (MeTHF) and THF as solvents in industrial processes where vapour phase exposure is unavoidable. Solvents shown in green are produced industrially from biorenewable sources, in yellow may be produced biorenewably but typically are not, and in red cannot be produced from renewable sources. No observed adverse effect concentrations (NOAECs) are taken from the European Chemicals Agency (ECHA) database and are calculated for workplace (except n-butylamine, BA, where the value for general population is used) exposure via inhalation of solvent vapours.