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. 2024 Nov 18;38(12):e70057. doi: 10.1002/jbt.70057

Figure 1.

Figure 1

EP 80317 reduces systemic and lung homogenate ROS and inflammatory mediators. (A) Study design. (B) Bar graphs and dot plots represent the relative expression of Igf1 mRNA in lung tissue of CD36+/+ and (F) CD36‐/‐ mice. (C) Mean plasma MDA levels of CD36+/+ and (G) CD36‐/‐ mice, expressed as bar graphs and dot plots. (D) Bar graphs and dot plots represent the relative expression of Nox2 mRNA in lung tissue of CD36+/+ and (H) CD36‐/‐ mice. (E) Bar graphs and dot plots of the total leucocytes recruitment in lung tissue by MPO assay of CD36+/+ and (I) CD36‐/‐ mice. (J) Bar graphs and dot plots represent the mononuclear cells count per mm2 of photomicrographs of lung tissue of CD36+/+ and (K) CD36‐/‐. (L) Representative photomicrographs of lungs after staining with hematoxylin‐eosin (scale bar: 100 μm). Data are mean ± SEM. *p < 0.05 and ***p < 0.001, as assessed by an unpaired t test. n = 6–11 per group for CD36+/+ and n = 6 per group for CD36‐/‐.