Figure 11.

Effect of uncertainty in melting temperature and heat of fusion on the SAFT-γ Mie description of the solid–liquid equilibrium (solubility) of glycine (2) in water (1) at 1 bar. (a) Sensitivity of the solubility calculations to the melting temperature for a fixed enthalpy of fusion of 22 J mol⁻¹; the black curve represents calculations using the reported melting temperature (569 K), whereas blue and red curves denote calculations using the maximum (578 K) and minimum (560 K) of the uncertainty range, respectively. (b) The sensitivity of solubility calculations to the enthalpy of fusion for a fixed melting temperature of 569 K; the black curve represents calculations using the reported enthalpy of fusion (22 kJ mol^–1) whereas blue and red curves denote calculations using the maximum (25 kJ mol^–1) and minimum (19 kJ mol^–1) of the uncertainty range, respectively. The symbols (circles) denote the experimental data.^22,80,81,84