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. 2024 Nov 20;21(1):2427751. doi: 10.1080/15502783.2024.2427751

Table 1.

Blood lipid response to maximal exercise.

        Time Point Mean      
Variable Treatment n PRE POST (SEM) Effect p-Value ηp2
Total Cholesterol PLA 15 207.3 ± 41.6 226.6 ± 44.2† 217.0 ± 9.7 T 0.000 0.870
(mg/dL) AX 15 197.8 ± 29.9 217.9 ± 33.2† 207.8 ± 9.7 G x T 0.783 0.003
  Total 30 202.6 ± 35.9 222.2 ± 38.6 212.4 ± 6.8      
Triglycerides PLA 15 130.9 ± 70.0 144.7 ± 67.2† 137.8 ± 14.7 T 0.000 0.558
(mg/dL) AX 15 117.7 ± 40.9 132.5 ± 45.0† 125.1 ± 14.7 G x T 0.827 0.002
  Total 30 124.3 ± 56.7 138.6 ± 56.5 131.4 ± 10.4      
HDL Cholesterol PLA 15 48.3 ± 7.8 53.4 ± 8.3† 50.9 ± 2.2 T 0.000 0.862
(mg/dL) AX 15 47.1 ± 8.4 51.9 ± 9.3† 49.5 ± 2.2 G x T 0.724 0.005
  Total 30 47.7 ± 8.0 52.6 ± 8.7 50.2 ± 1.5      
LDL Cholesterol PLA 15 134.0 ± 35.6 145.7 ± 38.5† 139.9 ± 8.6 T 0.000 0.819
(mg/dL) AX 15 127.7 ± 28.3 140.5 ± 30.3† 134.1 ± 8.6 G x T 0.628 0.008
  Total 30 130.8 ± 31.7 143.1 ± 34.2 137.0 ± 6.1      
Non-HDL Cholesterol PLA 15 159.0 ± 41.9 173.2 ± 45.3† 166.1 ± 10.0 T 0.000 0.835
(mg/dL) AX 15 150.7 ± 32.3 166.0 ± 35.3† 158.4 ± 10.0 G x T 0.670 0.007
  Total 30 154.9 ± 37.0 169.6 ± 40.1 162.2 ± 7.1      
VLDL Cholesterol PLA 15 25.0 ± 9.6 27.5 ± 10.4† 26.2 ± 2.1 T 0.000 0.567
(mg/dL) AX 15 23.1 ± 5.9 25.5 ± 6.7† 24.3 ± 2.1 G x T 1.000 0.000
  Total 30 24.0 ± 7.9 26.5 ± 8.6 25.3 ± 1.5      
LDL/HDL Ratio PLA 15 2.86 ± 0.89 2.81 ± 0.88 2.84 ± 0.23 T 0.118 0.085
  AX 15 2.83 ± 0.91 2.82 ± 0.87 2.82 ± 0.23 G x T 0.407 0.025
  Total 30 2.85 ± 0.88 2.82 ± 0.86 2.83 ± 0.16      
Total Cholesterol/HDL Ratio PLA 15 4.40 ± 1.09 4.35 ± 1.08 4.37 ± 0.27 T 0.137 0.077
  AX 15 4.34 ± 1.05 4.33 ± 1.01 4.34 ± 0.27 G x T 0.396 0.026
  Total 30 4.37 ± 1.05 4.34 ± 1.03 4.36 ± 0.19      

Data are expressed as means ± standard deviations for the placebo (PLA) and astaxanthin (AX) treatments. HDL = high-Density Lipoprotein; LDL = Low-Density Lipoprotein; VLDL = Very-Low Density Lipoprotein. Data were analyzed using a multivariate and univariate General Linear Model with repeated measures. P-levels, with partial ETA squared (ηp2) effect size, were reported. General Linear Model analysis revealed a significant overall Wilk’s Lambda for Time (p < 0.001, ηp2 = 0.905); however, no significant Treatment x Time (p = 0.958, ηp2 = 0.059) effect. Greenhouse-Geisser univariate p-levels are listed for time (T) and treatment x time (G x T) interaction effects. Significance was determined via pairwise comparison, with LSD posthoc adjustment, indicated as differences from baseline: † = p < 0.05 [‡ = p > 0.05 to p < 0.10]. ηp2 effect size values of 0.01–0.05 = small, 0.06–0.13 = medium, and > 0.14 = large.