Table 3.
Stratified protein/creatine ratio (PCR) data vs. 24-hUP according to renal function levels in three groups to compare correlation, coefficient of determination, the respective Youden point, and ROC curve analysis and Likelihood-ratio
| Variables | Total N = 217 |
Rs/ R2 | Cut-off by Youden Index | Sensitivity (%) |
Specificity (%) |
Area under ROC curve, SD (95%CI) | Likelihood-ratio |
|---|---|---|---|---|---|---|---|
| PCR vs 24-h global proteinuria | 217 (100%) | 0.86/0.45 | 0.77 | 91.0 | 86.5 | 0.95 ± 0.01 (0.92; 0.98) | LR + 6.7; LR- 0.1 |
| Degree of kidney function | |||||||
| 10 to < 30 mL/min | 54 (25%) | 0.83/0.35 | 0.76 | 86.4 | 90.0 | 0.95 ± 0.03 (0.85; 0.98) | LR + 8.6; LR- 0.15 |
| 30-60 mL/min | 55 (25%) | 0.88/0.56 | 0.83 | 93.3 | 90.0 | 0.94 ± 0.04 (0.84; 0.98) | LR + 9.3; LR- 0.07 |
| > 60 mL/min | 108 (50%) | 0.89/0.55 | 0.80 | 89.5 | 90.6 | 0.96 ± 0.01 (0.91; 0.99) | LR + 9.5; LR- 0.12 |
SD Standard Deviation, CI Confidence Interval, Rs Spearman's correlation coefficient, R2 Coefficient of determination, ROC Receiver operating characteristic, LR Likelihood-Ratio