Table 4.
Comparison by degree of urine protein, correlation analysis, ROC curve (sensitivity and specificity) and Likelihood-ratio (LR)
| Proteinuria Level (grams/day) | Total N = 217 |
Rs/ R2 | Cut-off by Youden Index | Sensitivity (%) |
Specificity (%) |
Area under ROC curve, SD (95% CI) | Likelihood-ratio |
|---|---|---|---|---|---|---|---|
| ≤ 0.3 g/day | 45 (21%) | 0.70/0.40 | 0.73 | 83.3 | 90.0 | 0.85 ± 0.09 (0.71; 0.94) | LR + 8.1; LR- 0.2 |
| > 0.3–3.5 g/day | 105 (48.3%) | 0.53/0.21 | 0.50 | 64.1 | 84.6 | 0.76 ± 0.06 (0.67; 0.84) | LR + 4.2; LR- 0.4 |
| > 3.5 g/day | 67 (30.8%) | 0.36/0.20 | – | – | – | – | – |
SD Standard Deviation, CI Confidence Interval, Rs Spearman's correlation coefficient, R2 Coefficient of determination, ROC Receiver operating characteristic, LR Likelihood-Ratio