Skip to main content
. 2024 Nov 22;24:456. doi: 10.1186/s12883-024-03958-9

Table 1.

Characteristic pathological subtypes of MM2-cortical-type sporadic creutzfeldt–jakob disease

Classification Prion Pathological change PrP deposition pattern
MM2C (lv) M2C (lv) Large vacuolation

Patchy-perivacuolar

PrP deposits

MM2C (sv) M2C (sv) Small vacuolation Synaptic PrP deposits

MM2C (lv + sv)

(reported case (7))

M2C (lv) and M2C (sv)

Large vacuolation and

small vacuolation

Perivascuolar and synaptic

PrP deposits

MM2C (lv + sv)

(This case)

M2C (lv) and M2C (sv) Small vacuolation

Patchy-perivacuolar and synaptic

PrP deposits

PrP, prion protein; lv, large vacuole; sv, small vacuole