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. 2024 Nov 22;22:551. doi: 10.1186/s12916-024-03764-7

Table 3.

Continuous outcomes in this meta-analysis with corresponding minimal clinically important difference (MCID). Each summary outcome measure was transformed back into natural units for comparison to the MCID [22]

Outcome (default measure) Meta-analysis pooled estimate Transformed to measure units MCID
Functional status (Barthel index) SMD 0.09 (0.02 to 0.16) 2.78 points (0.62 to 4.95) 9 to 18 points [39, 40]
Cognition (MMSE) MD 0.97 points (0.35 to 1.60) 0.97 points (0.35 to 1.60) 1.4 to 2.0 points [41, 42]
Mood (GDS) SMD −0.67 (−2.30 to 1.05) −2.18 points (−7.48 to 3.41) 5 points [43]
Quality of life (SF-36) SMD 0.09 (−0.11 to 0.28) 2.49 points (−3.04 to 7.74) 2 to 3 points [44]

SMD standardized mean difference, MD mean difference, MMSE mini-mental status examination, GDS geriatric depression scale, SF-36 36-item short form survey