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. 2024 Nov 22;14:29013. doi: 10.1038/s41598-024-79909-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Soluble inflammatory mediators (SIM) over time in SARS-CoV-2 and HCV cohorts. A logarithmic scale heatmap illustrating the concentrations of individual cytokines and chemokines relative to the corresponding median concentrations at different time points (T1-4). Dark blue represents decreased SIM concentrations, while dark brown indicates increased SIM concentrations. Healthy donor levels at T1 are maintained across all time points. T1 corresponds to baseline (start of therapy/positive PCR result), T2 = 3 months, T3 = 6 months, and T4 = 9 months. Notably, data for the long-term follow-up (T5) are presented for the chronic HCV cohort with cirrhosis, as T4 data is missing.