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. 2024 Nov 8;40:101841. doi: 10.1016/j.bbrep.2024.101841

Table 7.

In-vitro comparison of IC50 and % α-amylase inhibition for anti-diabetic activity in Leeamacrophylla leaf extracts with quercetin standard.

Fractions Conc. (μg/mL) % of α-amylase inhibitory
Inhibition of α-amylase (%) (Mean ± STD) IC50 (μg/mL)
a b c
LM1
10 13.53 13.55 13.50 13.53 ± 0.02 57.36
20 25.40 25.42 25.44 25.42 ± 0.02
40 49.44 49.48 49.44 49.45 ± 0.02
80 81.11 81.17 81.15 81.14 ± 0.03
160
92.55
92.51
92.50
92.52 ± 0.03
LM2
10 6.01 6.06 6.11 6.06 ± 0.05 100.66
20 13.88 13.60 13.66 13.71 ± 0.15
40 19.50 19.58 19.57 19.55 ± 0.02
80 40.33 40.36 40.35 40.35 ± 0.02
160
78.36
78.35
78.40
78.37 ± 0.03
LM3
10 7.14 7.14 7.17 7.15 ± 0.02 164.92
20 12.65 12.66 12.66 12.66 ± 0.01
40 20.07 20.14 20.12 20.11 ± 0.04
80 40.55 40.58 40.52 40.55 ± 0.03
160
43.48
43.47
43.55
43.50 ± 0.04
Quercetin (standard) 10 7.55 7.55 7.54 7.55 ± 0.01 97.45
20 11.11 11.10 11.10 11.10 ± 0.01
40 21.98 22.00 21.98 21.99 ± 0.01
80 41.88 41.87 41.87 41.87 ± 0.01
160 80.64 80.69 80.66 80.66 ± 0.03